Tauroursodeoxycholic Acid
ICETauroursodeoxycholic Acid (TUDCA) is a naturally occurring hydrophilic bile acid and the taurine conjugate of ursodeoxycholic acid. It plays a key role in liver protection, cellular health, and mitochondrial function. Its growing relevance in neurodegenerative disease research positions it as a valuable therapeutic candidate.
Applications
Tauroursodeoxycholic Acid is used primarily as an API in drug formulations targeting:
- Cholestatic liver diseases
- Ophthalmic conditions and metabolic disorders (under investigation)
End uses and Mechanism of Action
The primary use of TUDCA is as an active pharmaceutical and nutraceutical ingredient. It is used both as a digestive aid due to its choleretic effect and as an active pharmaceutical ingredient (API) in several pharmaceutical formulations. It supports liver health by promoting bile flow and protecting hepatocytes from apoptosis.
Additionally, TUDCA exhibits neuroprotective properties, making it valuable in the treatment of neurodegenerative diseases. Its role in reducing ER stress also positions it as a potential therapeutic agent in metabolic disorders.
- Product overview
- Manufacturing Sites
Product Overview
CAS Number
14605-22-2
Molecular Formula
C26H45NO6S
Molecular Weight
499.71
Synonyms
TUDCA, 3α,7β-Dihydroxy-5β-cholanoyltaurine, Ursodeoxycholyltaurine, Taurursodiol, ursodoxicoltaurine
INCHL
BHTRKEVKTKCXOH-LBSADWJPBX
UNII
60EUX8MN5X
Form
White Powder or White Microcrystalline Powder
Manufacturing Sites
Sites |
Grade |
Packaging |
Standard Specification |
GMP Compliant |
DMF Available |
Chemical CEP |
BSETSE CEP |
|---|---|---|---|---|---|---|---|
Basaluzzo - Italy |
N/A |
25 kg polyethylene/heat-sealed aluminium bags in a fibre drum |
Available on request |
Yes |
Yes |
No |
Yes |