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We offer a comprehensive custom synthesis service to take your project from discovery to clinical trial

Dextra

Our business unit Dextra specializes in Carbohydrate chemistry

Dextra, provides innovative synthetic solutions to the synthesis of carbohydrates and other complex molecules, frequently reducing the number of synthetic steps required to access the target compound.

Core competencies include complex oligosaccharide chemistry, route design, process development, optimisation and scale-up, process validation, technology transfer and GMP manufacture for Phase 1 and Phase 2 clinical trials.

Our fully equipped analytical laboratories offer expert support with a comprehensive range of analytical techniques available. All activities are fully supported by a strong Quality Management System and Health & Safety Framework and we have successfully achieved ISO9001:2015 registration.

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Analytical Services

Working collaboratively to provide end-to-end support across the project life-cycle.

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Discovery Chemistry

We’ll evaluate candidate structures, provide expert advice on synthetic viability, and complete the synthesis of early targets.

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Route Scouting

We design synthetic routes and evaluate their viability with longer term goals of efficient, sustainable and robust process in mind.

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Process development

During process optimisation, we develop appropriate purging points through the use of techniques such as crystallisation.

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Tox Batches

We understand the importance of manufacturing material with an impurity profile suitable for IND enabling studies.

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GMP Manufacturing

At our Reading site we offer full cGMP manufacturing to support phase 1 and phase 2 clinical trials.

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