Cholic acid
ICE NZPCholic acid is a primary human bile acid and is one of the two major bile acids produced by the liver (the other being chenodeoxycholic acid), where it is synthesized from cholesterol. It appears in bile as either its glycine or taurine conjugates.
ICE Pharma manufactures two high purity grades (an Intermediate and API Grade) of GMP compliant cholic acid from bovine bile. Our robust extraction/purification process yields multi-tonne quantities of GMP cholic acid with full traceability and BSE/TSE legislation compliance.
- Product overview
- End Uses
- Manufacturing Sites
Products Overview
CAS Number
81-25-4
EC Number
201-337-8
Molecular Formula
C24H40O5
Molecular Weight
408.57
Synonyms
3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid
MDL Number
MFCD00003672
INCHL
BHQCQFFYRZLCQQ-OELDTZBJSA-N
UNII
G1JO7801AE
Form
white powder or white microcrystalline powder
End Uses
The primary use of cholic acid is as a pharmaceutical intermediate for the manufacture of ursodeoxycholic acid (UDCA), an API used for several indications including the treatment and prevention of liver diseases and the dissolution of gall stones. Cholic acid is also used as an API to treat inborn errors of bile acid metabolism.
Manufacturing Sites
Sites |
Grade |
Packaging |
Standard Specification |
GMP Compliant |
DMF Available |
Chemical CEP |
BSETSE CEP |
|---|---|---|---|---|---|---|---|
New Zealand |
Intermediate |
25 kg polyethylene plastic/foil liner in Darbox |
Available on request |
Yes |
No |
No |
Yes |
New Zealand |
API |
25 kg polyethylene plastic/foil liner in Darbox |
Available on request |
Yes |
Yes |
No |
Yes |