Deoxycholic Acid

Overview

Deoxycholic Acid is a naturally occurring secondary bile acid produced in the human intestine through bacterial action on primary bile acids. It plays a critical role in the emulsification and absorption of dietary fats, making it a valuable compound in pharmaceutical, cosmetic, and research applications.

Product Description

ICE Pharma manufactures high-quality deoxycholic acid in three grades: standard, pharma grade, and enhanced high-purity grade. Our production process follows stringent GMP guidelines, ensuring consistency, safety, and superior quality. Sourced from bovine and/or ovine bile, our deoxycholic acid undergoes a rigorous extraction and purification process.

Applications

Deoxycholic acid is widely used across various industries due to its unique properties:

• Pharmaceuticals: Historically used as a raw material in the synthesis of corticosteroids.
• Cosmetics: FDA-approved for reducing submental fat, enhancing facial aesthetics.
• Biological Research: Functions as a biological detergent, enabling cell lysis and solubilization of cellular and membrane components.
• Excipient: Used as a permeation enhancer, solubilizer and/or stabiliser to increase bioavailability of drug substances.
• In-vitro Diagnostics: Used as an ingredient in microbiological culture media to aid in isolation of gram-negative microorganisms.

Deoxycholic Acid Injection

Deoxycholic acid injection is an FDA-approved, non-surgical treatment for reducing localized fat deposits, particularly in the submental (double chin) area. It works by breaking down fat cells, which are then naturally eliminated by the body. This minimally invasive procedure has gained popularity in aesthetic medicine as an effective alternative to liposuction.

• Uses: Primarily used in cosmetic treatments to contour and refine areas with stubborn fat deposits.
• Mechanism of Action: Deoxycholic acid disrupts adipocyte cell membranes, leading to fat cell destruction and absorption.
• Administration: Typically administered in a series of injections by trained medical professionals.

Manufacturing and Quality Assurance

Our deoxycholic acid API is produced in a state-of-the-art facility in Basaluzzo (AL), Italy, ensuring the highest standards of quality and compliance:

• Facility: GMP-compliant production site.
• Packaging: Available in 25 kg containers for convenient handling and transportation, or in bespoke pack sizes for enhanced high-purity grade.
• Certifications: GMP-certified, with Drug Master File (DMF) and Chemical Certificate of Suitability (CEP) available upon request.

Safety and Handling

• Form: White crystalline powder.
• Handling: Recommended to be used in a well-ventilated area with appropriate personal protective equipment.