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Sodium taurocholate

ICE NZP

Sodium taurocholate (NaTC) is the taurine conjugate of cholic acid. This water soluble bile acid conjugate is manufactured by ICE Pharma from ICE’s own cholic acid extracted from bovine bile. This semi-synthetic NaTC is chemically identical to the natural steroid produced in the liver of many animal species.

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  • Product overview
  • End Uses
  • Manufacturing Sites

Products Overview

  • CAS Number

    145-42-6

  • EC Number

    205-653-7

  • Molecular Formula

    C26H44NNaO7S

  • Molecular Weight

    537.69

  • Synonyms

    Taurocholic acid sodium salt

  • MDL Number

    MFCD00013050

  • INCHL

    JAJWGJBVLPIOOH-IZYKLYLVSA-M

  • UNII

    M6N3TH81NO

  • Form

    White to off-white powder

End Uses

It is a powerful biological detergent and may be used to dissolve lipids and to free membrane bound proteins. It is a bacteriology culture media ingredient and used in some forms of MacConkey’s broth. It can also accelerate lipase activity. It has potential in the manufacture of vaccines and as a vehicle to assist with drug and vaccine delivery. The USP recommends the use of sodium taurocholate as a component in biorelevant gastrointestinal media to be used for the dissolution testing of drugs. Information gained from tests supports predictions of in vivo absorption behaviour.

Manufacturing Sites

Sites
Grade
Packaging
Standard Specification
GMP Compliant
DMF Available
Chemical CEP
BSETSE CEP

New Zealand

N/A

1 kg, 5 kg polyethylene plastic liner or foil pouch in a circular pail with lid

N/A

Yes

No

No

Yes

Basaluzzo - Italy

N/A

10 kg polyethylene/heat-sealed aluminium bags in a fibre drum

N/A

Yes

No

No

Yes

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