Ursodeoxycholic Acid
ICE Raichem ICE JapanUrsodeoxycholic acid is a bile acid used for the treatment of primary biliary cirrhosis (PBC), dissolution of radiolucent gallstones in patients with a functioning gallbladder, and treatment of hepatobiliary disorders associated with cystic fibrosis in pediatric patients.
- Product overview
- End Uses
- Manufacturing Sites
Products Overview
CAS Number
128-13-2
EC Number
99 128-13-2.
Molecular Formula
C24-H40-O4
Molecular Weight
392.576
Synonyms
17-beta-(1-Methyl-3-carboxypropyl) etiocholane-3-alpha,7-beta-diol
MDL Number
MFCD00003680
INCHL
RUDATBOHQWOJDD-UZVSRGJWSA-N
Form
White Crystalline Powder
Available for Export
Yes
End Uses
Ursodeoxycholic acid reduces elevated liver enzyme levels by facilitating bile flow through the liver and protecting liver cells. The main mechanism is anticholelithic. Although the exact process of ursodiol's antichol elithic action is not entirely understood, it is thought that the drug is concentrated in bile and decreases biliary cholesterol by suppressing hepatic synthesis and secretion of cholesterol and by inhibiting its intestinal absorption. The reduced cholesterol saturation permits the gradual solubilization of cholesterol from gallstones, resulting in their eventual dissolution.
Manufacturing Sites
Sites |
Grade |
Packaging |
Standard Specification |
GMP Compliant |
DMF Available |
Chemical CEP |
BSETSE CEP |
|---|---|---|---|---|---|---|---|
Basaluzzo - Reggio Emilia (Italy) |
N/A |
25kg |
N/A |
Yes |
Yes |
Yes |
Yes |
Raichem (India) |
N/A |
25kg |
N/A |
Yes |
Yes |
Yes |
Yes |
Iwaki (Japan) |
N/A |
25kg |
N/A |
Yes |
Yes |
Yes |
Yes |