Active Pharmaceutical Ingredients

Chenodeoxycholic acid is a primary bile acid. In nature it primarily exists as either its glycine or taurine conjugate. It is manufactured by ICE Pharma via chemical synthesis from bovine derived raw materials. ...

Cholic acid is a primary human bile acid and is one of the two major bile acids produced by the liver (the other being chenodeoxycholic acid), where it is synthesized from cholesterol. It appears in bile as either its glycine or taurine conjugates. ICE Pharma manufactures two high purity grades (an ...

Dehydrocholic Acid (DHCA) is a bile acid that does not occur naturally manufactured by ICE Pharma via semi-synthetic process. ...

In nature, deoxycholic acid is referred to as a “secondary bile acid”, is produced in the intestine from the salts of glycocholic and taurocholic acid by the action of bacterial enzymes. ICE Pharma manufactures three grades (standard, an high purity and Halal grade) of GMP compliant deo...

Doxofylline is a methylxanthine bronchodilator with potent bronchodilator activity comparable to that of theophylline. In animal studies, doxofylline demonstrated to attenuate bronchoconstriction, inflammatory actions and the release of thromboxane A2 (TXA2) when challenged with platelet-activating ...

Inosine Pranobex is an alkylamino-alcohol complex of inosine used in the treatment of a variety of viral infections. Unlike other antiviral agents, it acts by modifying or stimulating cell-mediated immune processes rather than action on the virus directly. ...

A 50:50 mixture of Ursodeoxycholic and Chenodeoxycholic acids as their mixed magnesium salt. Using our existing bovine derived bile acid API’s, ICE Pharma manufactures this trihydrated salt of CDCA and UDCA in a crystalline form. ...

Sodium dehydrocholate is the sodium salt of dehydrocholic acid. It is manufactured by ICE Pharma from our high purity dehydrocholic acid. ...

Tauroursodeoxycholic acid (TUDCA), a naturally occurring hydrophilic bile acid, is the taurine conjugate of ursodeoxycholic acid. ICE Pharma manufactures this active pharmaceutical ingredient under GMP conditions from our high purity ursodeoxycholic acid.  Our robust process yields multi-tonne quan...

Ursodeoxycholic acid is a bile acid used for the treatment of primary biliary cirrhosis (PBC), dissolution of radiolucent gallstones in patients with a functioning gallbladder, and treatment of hepatobiliary disorders associated with cystic fibrosis in pediatric patients. ...