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Excipients

Essential for the manufacture of drug products, bile acids are widely used as excipients in their formulation.

Cholic Acid

Cholic Acid

ICE NZP

Overview ICE Pharma is a leading manufacturer of Cholic Acid API, a primary human bile acid synthesized from cholesterol in the liver. It is one of the two major bile acids produced by the liver (the other being chenodeoxycholic acid), where it appears in bile as either its glycine or taurine conjug...

deoxycholic acid chemical structure

Deoxycholic Acid

ICE

Overview Deoxycholic Acid is a naturally occurring secondary bile acid produced in the human intestine through bacterial action on primary bile acids. It plays a critical role in the emulsification and absorption of dietary fats, making it a valuable compound in pharmaceutical, cosmetic, and researc...

Glycocholic Acid

Glycocholic Acid

ICE

Overview Glycocholic Acid (GCA) is the glycine conjugate of cholic acid and one of the primary bile acid components in human bile. The amphiphilic nature of Glycocholic acid – meaning it has both hydrophilic and hydrophobic regions – making it ideal for micelle formation, fats and vitami...

Lithocholic Acid

Lithocholic Acid

ICE

Lithocholic Acid (LCA) is a secondary human bile acid, produced in the gut by microbial action on chenodeoxycholic acid. High purity LCA is produced by ICE Pharma through a semi-synthetic process. ...

Sodium Cholate

Sodium Cholate

ICE NZP

Overview Sodium Cholate (NaC) is the sodium salt of Cholic Acid, the most abundant bile acid naturally found in human bile. As an amphiphilic compound, it plays a key role in solubilizing lipids and enhancing drug absorption. ICE Pharma produces high-purity, GMP-compliant Sodium Cholate through a ro...

Sodium Dehydrocholate

Sodium Dehydrocholate

ICE

At ICE Pharma, we are a leading global manufacturer and supplier of Sodium Dehydrocholate, a synthetic bile acid renowned for its efficacy in stimulating bile flow and aiding in the digestion of fats. Our Sodium Dehydrocholate is synthesized under stringent Good Manufacturing Practice (GMP) conditio...

Sodium Deoxycholate

Sodium Deoxycholate

ICE NZP

Sodium deoxycholate is the sodium salt of deoxycholic acid, and is water-soluble. ICE Pharma manufactures high purity GMP compliant sodium deoxycholate from bovine bile through a robust extraction/purification process. ...

Sodium Glycocholate

Sodium glycocholate

ICE

Overview Sodium Glycocholate (NaGC) is the sodium salt of Glycocholic Acid, a naturally occurring bile acid conjugate of glycine and cholic acid. As an amphiphilic bile salt, NaGC offers surfactant properties relevant for fat emulsification, vitamins and drugs solubilisation and drug permeation acro...

Sodium Taurocholate

Sodium taurocholate

ICE NZP

Overview Sodium Taurocholate (NaTC) is the taurine conjugate of cholic acid, a water-soluble bile acid naturally produced in the liver of many animal species. As amphiphilic compound, the bile salt NaTC is used to improve the solubility, stability, permeation across biological membrane of drugs. ICE...

Sodium Taurodeoxycholate

Sodium Taurodeoxycholate

ICE

Overview Sodium Taurodeoxycholate (NaTDC) is the sodium salt of taurine conjugate of deoxycholic acid (DCA), a naturally occurring secondary bile acid. As amphiphilic compound, NaTDC is effective to increase the bioavailability of drugs due to enhancing the solubility and permeation across biologica...