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Intermediates

We manufacture a range of bulk pharmaceutical intermediates for supply to pharmaceutical and biotechnology companies worldwide.

Bile powder

ICE

Product derived from drying of pure bovine bile ...

Cholic acid

ICE NZP

Cholic acid is a primary human bile acid and is one of the two major bile acids produced by the liver (the other being chenodeoxycholic acid), where it is synthesized from cholesterol. It appears in bile as either its glycine or taurine conjugates. ICE Pharma manufactures two high purity grades (an ...

Lithocholic acid

ICE

Lithocholic acid (LCA) is a secondary human bile acid, produced in the gut by microbial action on chenodeoxycholic acid. High purity LCA is produced by ICE Pharma through a semi-synthetic process. ...

N-Acetyl-D-Mannosamine

NZP

N-Acetyl-D-mannosamine, manufactured according to cGMP at our NZP site is a rare monosaccharide involved in a range of metabolic processes. It is often used as a precursor in the chemical or enzymatic synthesis of the neuraminic acids found in glycolipids and glycoproteins. In biological systems it ...

Sodium Cholate

ICE NZP

Sodium cholate is a water soluble sodium salt of cholic acid, the most prevalent bile acid in human bile. ICE Pharma manufactures high purity GMP compliant sodium cholate from bovine bile through a robust extraction/purification process. ...

Sodium glycocholate

ICE

Sodium glycocholate is the sodium salt of glycocholic acid. ...

Sodium taurocholate

ICE NZP

Sodium taurocholate (NaTC) is the taurine conjugate of cholic acid. This water soluble bile acid conjugate is manufactured by ICE Pharma from ICE’s own cholic acid extracted from bovine bile. This semi-synthetic NaTC is chemically identical to the natural steroid produced in the liver of many ...

Sodium Taurodeoxycholate

ICE

Sodium taurocholate is the taurine conjugate of deoxycholic acid (DCA). This water soluble bile acid conjugate is manufactured by ICE Pharma from ICE’s own high purity DCA and is chemically identical to the natural form. ...