Intermediates

Product derived from drying of pure bovine bile ...

Overview ICE Pharma is a leading manufacturer of Cholic Acid API, a primary human bile acid synthesized from cholesterol in the liver. It is one of the two major bile acids produced by the liver (the other being chenodeoxycholic acid), where it appears in bile as either its glycine or taurine conjug...

Lithocholic Acid (LCA) is a secondary human bile acid, produced in the gut by microbial action on chenodeoxycholic acid. High purity LCA is produced by ICE Pharma through a semi-synthetic process. ...

N-Acetyl-D-mannosamine, manufactured according to cGMP at our NZP site is a rare monosaccharide involved in a range of metabolic processes. It is often used as a precursor in the chemical or enzymatic synthesis of the neuraminic acids found in glycolipids and glycoproteins. In biological systems it ...

Overview Sodium Cholate (NaC) is the sodium salt of Cholic Acid, the most abundant bile acid naturally found in human bile. As an amphiphilic compound, it plays a key role in solubilizing lipids and enhancing drug absorption. ICE Pharma produces high-purity, GMP-compliant Sodium Cholate through a ro...

Overview Sodium Glycocholate (NaGC) is the sodium salt of Glycocholic Acid, a naturally occurring bile acid conjugate of glycine and cholic acid. As an amphiphilic bile salt, NaGC offers surfactant properties relevant for fat emulsification, vitamins and drugs solubilisation and drug permeation acro...

Overview Sodium Taurocholate (NaTC) is the taurine conjugate of cholic acid, a water-soluble bile acid naturally produced in the liver of many animal species. As amphiphilic compound, the bile salt NaTC is used to improve the solubility, stability, permeation across biological membrane of drugs. ICE...

Overview Sodium Taurodeoxycholate (NaTDC) is the sodium salt of taurine conjugate of deoxycholic acid (DCA), a naturally occurring secondary bile acid. As amphiphilic compound, NaTDC is effective to increase the bioavailability of drugs due to enhancing the solubility and permeation across biologica...