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胆酸钠

ICE NZP

概述

Sodium Cholate (NaC) is the sodium salt of Cholic Acid, the most abundant bile acid naturally found in human bile. As an amphiphilic compound, it plays a key role in solubilizing lipids and enhancing drug absorption.

ICE Pharma produces high-purity, GMP-compliant Sodium Cholate through a robust extraction and purification process using bovine bile as the natural source. This ensures pharmaceutical-grade consistency and performance across industrial and life science applications.

应用

Sodium Cholate is a versatile bile salt with several established applications:

  • Microbiological Media: used in the formulation of selective diagnostic media, particularly for cultivating intestinal bacteria.
  • Protein Extraction & Purification: functions as a manufacturing aid in bioprocessing workflows, helping extract and stabilize membrane proteins.
  • Pharmaceutical Formulations: NaC acts as stabilizer, solubilizer and permeation enhancer excipient, thus resulting as a bioavailability enhancer in in several routes of administration.

最终用途

Sodium Cholate is used in a variety of scientific and pharmaceutical applications. It plays a key role in the preparation of microbiological diagnostic media, particularly for cultivating and identifying intestinal microorganisms. In biomanufacturing, it serves as a processing aid for the extraction and purification of proteins, especially membrane-bound proteins.

Additionally, Sodium Cholate is used as an excipient in certain drug formulations to improve the bioavailability of drugs through micelle formation or formulating various drug delivery systems.

制造与质量保证

Our high-purity Sodium Cholate is manufactured at ICE Pharma’s state-of-the-art facilities in Italy and New Zealand, operating under stringent GMP standards. Each batch undergoes rigorous quality control to ensure high purity, consistency, and safety.

合规

Our commitment to quality, compliance, and safety ensures that our Sodium Cholate meets global pharmaceutical industry standards, making it a reliable choice for pharmaceutical applications worldwide.

  • 符合GMP标准:
  • DMF Available: Yes (API grade), Yes (excipient Japanese DMF)
  • BSE/TSE CEP: Yes, of the starting material

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产品概述

  • CAS号

    361-09-1, 206986-87-0 (sodium cholate hydrate)

  • EC编号

    206-643-5

  • 分子式

    C24H39NaO5

  • 分子量

    430.56

  • 同义词

    3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholic acid sodium salt

  • MDL编号

    MFCD00064138, MFCD00150749 (sodium cholate hydrate)

  • INCHL

    NRHMKIHPTBHXPF-TUJRSCDTSA-M

  • UNII

    NU3Y4CCH8Z

  • 表单

    white powder or white microcrystalline powder

最终用途

Sodium cholate is used in the preparation and formulation of certain microbiological diagnostic media. It is used as a manufacturing aid for the extraction and purification of proteins. It is also used as an excipient in certain drug formulations to improve drug bioavailability.

生产基地

网站
年级
包装
Standard Specification
符合GMP标准
DMF 可用
化学CEP
BSETSE CEP

新西兰

不适用

20 kg polyethylene plastic/foil liner in Darbox

不适用

是的

是的

巴萨卢佐 - 意大利

不适用

10 kg polyethylene/heat-sealed aluminium bags in a fibre drum

不适用

是的

是的

是的

Reggio Emilia - Italy

不适用

25 kg double polyethylene bags in a fibre or plastic drum

不适用

是的

是的

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