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甘胆酸钠

ICE

概述

Sodium Glycocholate (NaGC) is the sodium salt of Glycocholic Acid, a naturally occurring bile acid conjugate of glycine and cholic acid. As an amphiphilic bile salt, NaGC offers surfactant properties relevant for fat emulsification, vitamins and drugs solubilisation and drug permeation across biological membranes.

ICE Pharma manufactures high-purity Sodium Glycocholate suitable for regulated pharmaceutical use. It is produced under stringent quality controls to ensure consistent performance, safety, and GMP compliance, ideal for injectable and parenteral formulations.

应用

Sodium Glycocholate is primarily used as a solubilizing and permeation enhancer agent to increase bioavailability of drugs in pharmaceutical formulations: with additional applications in drug delivery research:

  • Injectable Drug Formulations – NaGC is widely used in parenteral formulations due to its ability to form mixed micelles, improving solubility and stability of hydrophobic active ingredients.
  • Oral and Transmucosal drug delivery – NaGC supports enhanced solubilization of poor soluble drugs, absorption and permeability across mucosal membranes, making it suitable for oral suspensions and transmucosal applications.

最终用途

Sodium Glycocholate is primarily used as an excipient in injectable drug formulations. Like its parent compound glycocholic acid, it functions as a biocompatible and endogenous surfactant, capable of forming mixed micelles. These micelles enhance the solubility and bioavailability of poorly water-soluble drugs, making NaGC highly valuable in advanced drug delivery systems, throughout several routes of administration.

制造与质量保证

Our high-purity Sodium Glycocholate is manufactured at ICE Pharma’s state-of-the-art facility in Italy, operating under stringent GMP standards. Each batch undergoes rigorous quality control to ensure high purity, consistency, and safety.

合规

Our commitment to quality, compliance, and safety ensures that our Sodium Glycocholate meets global pharmaceutical industry standards, making it a reliable choice for pharmaceutical applications worldwide.

  • 符合GMP标准:
  • DMF Available: No
  • BSE/TSE CEP: Yes, for the staring material

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产品概述

  • CAS号

    863-57-0 and 338950-81-5

  • EC编号

    212-730-9

  • 分子式

    C26H42NO6Na

  • 分子量

    487,62

  • 同义词

    N-[(3α,5β,7α,12α)-3,7,12-trihydroxi-24-oxocholan-24-il)]glycin sodium salt

  • INCHL

    OABYVIYXWMZFFJ-ZUHYDKSRSA-M

  • 表单

    白色结晶粉末

最终用途

As with its parent compound it is primarily used as an excipient in injectable formulations as it is a powerful endogenous and biocompatible surfactant with the ability to form mixed micelles.

生产基地

网站
年级
包装
Standard Specification
符合GMP标准
DMF 可用
化学CEP
BSETSE CEP

巴西卢佐(AL),意大利

不适用

20kg

不适用

是的

是的

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